Longitudinal study of delayed cerebral ischemia in mice using daily functional ultrasound (fUS) imaging and gait analysis
Barthe Louis, Clement Rombi, Samuel Le Meur-Diebolt, Jean-Charles Mariani, Aurelien Mazeraud, Zsolt Lenkei · FENS Forum 2024
Delayed Cerebral Ischemia (DCI), is a complication of sub-Arachnoïdal Hemorrhage (sAH) associated with a high mortality and morbidity, which is responsible for heavy impairments on survivors. DCI is a slow developing pathology and its diagnosis requires concomitant monitoring of functional or motor deficits and brain perfusion or lesions. In our study we aim, after the development and validation of a preclinical DCI model, to investigate the utility of functional ultrasound (fUS) imaging for longitudinal monitoring of DCI. First we have adapted and refined a rodent model for the minimally-inva
ePoster · Neuroscience