TRPV1 enhances encoding of sensory information in mouse primary somatosensory cortex
Leena Amrutha, Ehsan Arabzadeh, Ehsan Kheradpezhouh · FENS Forum 2024
TRP Vanilloid 1 (TRPV1) is a member of the TRP superfamily that is involved in the modulation of diverse sensations across species from reptiles to humans. In mammals, TRPV1 is predominantly known for its role in the peripheral nervous system as a modulator of noxious and thermal stimuli. However, there is limited knowledge about the role of this sensory channel in the Central Nervous System. Here, we investigated the function of cortical TRPV1 in sensory processing and detection. We implemented a whisker-based vibration detection task to explore the impact of TRPV1 on sensory perception, usin
ePoster · Neuroscience