Choroid plexus volume as a proxy for neuroinflammation – evaluation of its trans-diagnostic, prognostic, and therapeutic biomarker potential in parkinsonism
Liucija Vaicenaviciute, Lennart Spindler, Kirsten Scott, Caroline Williams-Gray · FENS Forum 2024
Neurodegenerative disorders have a substantial immune component, implicating both peripheral and central immune systems. Despite neuroinflammation being linked to greater dementia risk, the interaction of central and peripheral inflammatory processes to influence disease courses remain ill-understood. A key site-of-interest for this interaction is the choroid plexus. Beyond secreting cerebrospinal fluid (CSF), it has been proposed as a gateway for peripheral immune cell entry into the central nervous system (CNS). As such, increases in choroid volume measurable with structural magnetic resonan
ePoster · Neuroscience