Topic: two alternative choice task

Adaptive behavior in a dynamically changing environment requires learning the value of actions, and updating these values in response to changes in the environment. Several studies have investigated the role of the striatum, and its key neuromodulators, dopamine (DA) and acetylcholine (Ach), in this process. However, these studies usually investigated these neuromodulatory signals in animals which had undergone extensive pre-training, and were thus experts at flexibly adapting to new action values. In addition, most of these studies did not explore the dynamics of these signals simultaneously,