Topic: two-tone discrimination task

Corticocollicular (CC) projections arise in deep layers of the auditory cortex and modulate upstream auditory information in the inferior colliculus (IC), forming feedback loops. They are crucially involved in auditory-related learning and frequency response modulations in auditory brainstem. Through widefield and 2-photon calcium imaging in awake mice we prior were able to show that layer 5 CC neurons display only a subtle topographic organization when compared to other layer 5 neuron types (Schmitt et al., 2023, Front Neural Circuit). However, these data were acquired under passive listening