Topic: urine scent mark test

To develop new therapeutic options for the treatment of bipolar disorder, animal models are a valuable tool to understand underlying changes in neurobiology. By manipulating the prefrontal dopamine D1 receptor our group was able to induce mania- as well as depressive-like behavior in rats. As social behavior is largely affected in bipolar disorder, we aim to phenotype our model in this respect. Therefore, a test battery including social hierarchy in three different tests (social dominance tube test, food competition test, urine scent mark test), sexual motivation and sexual behavior in adult r