fMRI study reveals enhanced top-down and bottom-up processes in schizophrenia
Shuhei Hara, Keita Suzuki, Akio Murakami, Kei Majima, Mohamed Adbelhack, Fan Cheng, Hidehiko Takahashi, Kenji Doya · COSYNE 2025
In schizophrenia, disrupted perceptual processes are attributed to both hallucinations and delusions in positive symptoms [1, 2]. However, it remains unclear how top-down and bottom-up processes are represented across a visual hierarchy related to distinct symptoms, such as hallucinations, delusions, and negative symptoms. Our goal is to identify the visual areas involved in aberrant top-down and bottom-up processes that contribute to distinct symptoms in schizophrenia. To investigate this, we conducted a functional magnetic resonance imaging (fMRI) experiment with a perceptual decision-making
ePoster · Neuroscience