Culturing postnatal mouse neurons of the deep cerebellar nuclei to investigate the functional expression of TRP ion channels in the cerebellum
Violeta Maria Caragea, Tudor Selescu, Alexandru Babes · FENS Forum 2024
The deep cerebellar nuclei (DCN) are the principal output structure of the cerebellum, carrying the information sent by the Purkinje cells from the cerebellar cortex to extra-cerebellar structures. Although circuits recruiting the DCN were shown to modulate multiple motor and nonmotor functions, the mechanisms facilitating excitability and neurotransmission at their projection neurons are poorly understood. Various Transient Receptor Potential (TRP) ion channels were shown to regulate neuronal activity in the cerebellar cortex, whereas the characterization of their functional roles in the DCN
ePoster · Neuroscience