Topic: vasopressin secretion

Maintenance of appropriate body hydration is controlled by the brain and is essential to preserve extracellular fluid volume and tonicity. Upon dehydration, osmotic homeostasis is restored through coordinated responses such as thirst (to promote water intake) and vasopressin secretion (to promote water reabsorption by the kidneys). In addition to these responses, dehydration is known to suppress appetite. This dehydration-induced anorexia is a highly adaptive response to prevent the absorption of osmolytes from food. In this project, we aim to identify the stimuli and neural mechanisms driving