Topic: vestibular dysfunction

The sense of orientation in space is crucial for survival and navigation in the environment. The brain derives spatial orientation from (1) self-motion signals originating in the vestibular system of the inner ear and (2) visual signals encoding orientation relative to external landmarks. Previous studies in animal models have shown that spatial orientation is compromised after vestibular lesions, but the relationship between partial lesions and the degree of functional impairment has not been established.In the present study, navigation and spatial orientation capacities were tested in a modi