Neuroanatomical characterisation of the cell adhesion molecule IgSF9b reveals heterogeneous synaptic localization across different regions of the mouse brain
Federico Rotondo, Heba Ali, Maxim Maichle, Michael Schmeisser, Nils Brose, Dilja Krueger-Burg · FENS Forum 2024
Immunoglobulin superfamily member 9b (IgSF9b) is a cell adhesion protein that has been linked to the etiology of several psychiatric disorders, including bipolar disorder and schizophrenia. Based on previous studies in neuronal cultures, IgSF9b was proposed to specifically regulate the structure and function of GABAergic synapses in the brain through an indirect interaction with the synaptic adhesion protein Neuroligin-2. To date, however, very little is known about the expression pattern of IgSF9b in the intact brain, and the synaptic localization of IgSF9b in different brain regions has neve
ePoster · Neuroscience