Optogenetic inhibition of parvalbumin interneurons in the medial striatum during a perceptual decision-making task
Anne Lorenz, Oriana Lavielle, Eric Burguiere · FENS Forum 2024
Decision-making can be defined as cognitive process based on the selection of a goal-directed action from a set of choices. In perceptual decision-making, this behavior guiding choice relies on sensory information. The associative part of the striatum has been proposed to be essential for such decision-making processes, in particular to select the appropriate action plan according to the sensory evidence. Parvalbumin interneurons (PVI) in the associative striatum may have a crucial role in this action plan selection despite their low numbers. Indeed, by inhibiting striatal processing, PVI may
ePoster · Neuroscience