Visual activity enhances neuronal excitability in thalamic relay neurons
Dominique Debanne, Maël Duménieu, Laure Molinieres, Loïs Naudin, Cécile Bonnaure, Anushka Wakade, Emilie Zanin, Aurore Aziz, Danièle Denis, Béatrice Marquèze-Pouey, Romain Brette, Michael Russier · FENS Forum 2024
The dorsal lateral geniculate nucleus (dLGN) has long been held to act as a basic relay for visual information travelling from the retina to cortical areas, but recent findings suggest a largely underestimated functional plasticity of dLGN neurons. However, the cellular mechanisms supporting this functional plasticity have not been yet explored. In particular, it remains to elucidate whether intrinsic neuronal excitability change upon visual stimuli. We show here that monocular deprivation for 10 days reduces the intrinsic excitability of dorsal LGN relay cells. Furthermore, dLGN neurons exhib
ePoster · Neuroscience