Impact of restless leg syndrome severity on cognitive function and depression
Erika Driver-Dunckley, Kartik Mangipudi, Nan Zhang, Charles Adler, Holly Shill, Geidy Serrano, Lucia Sue, Shyamal Mehta, Christine Belden, Ali Atri, Tom Beach · FENS Forum 2024
To determine whether cognitive dysfunction and depression are more prevalent in restless leg syndrome (RLS) subjects compared to controls and the impact of RLS severity on these variables. A prospective study was performed on 681 subjects (161 with RLS). The RLS group was subdivided into three subgroups of mild, moderate and severe based on International RLS Study Group (IRLSSG) score. General linear regression adjusted for age, sex and education was performed to evaluate for association between controls, RLS subgroups and outcomes. Analysis of cognitive functioning demonstrated a significant
ePoster · Neuroscience