Computation Within and Beyond the Brain - Uncovering Brain-Body-Wide Communication Networks through Imaging Cellular Activity of All Cells in a Vertebrate
Virginia Ruetten, Wei Zheng, Paul Tillberg, Guoqiang Yu, Maneesh Sahani, Misha Ahrens · COSYNE 2025
Animals are dynamical systems possessing a wide range of capabilities mediated by interactions between their constitutive cells. The brain, central integrator and coordinator of bodily output, solves problems in the context of bodily needs, driven by external environmental signals and internal bodily signals. While neuroscience has progressed in the ability to measure neurons and environment at ever great scale and resolution, our ability to measure activity within the rest of the body and relate these to neuronal computation remains limited. Here, we extend the principles and tools of neurosc