Distinct roles of cortical layer 5 subtypes in associative learning
Sara Moberg, Michele Garibbo, Camille Mazo, Ariel Gilad, Dietmar Schmitz, Rui Ponte Costa, Matthew Larkum, Naoya Takahashi · COSYNE 2025
Adaptive behavior is critically dependent on associative learning, where environmental cues are linked with subsequent positive or negative outcomes. At the core of this process, primary neocortical sensory areas serve as pivotal nodes, processing stimuli and distributing information to cortical and subcortical networks. Layer 5 (L5) of the cortex comprises two types of pyramidal projection neurons---intratelencephalic (IT) and extratelencephalic (ET) neurons---each with distinct downstream targets. Sensory cortex exhibits plastic changes after forming a sensory-reward association and L5 neuro
ePoster · Neuroscience