Topic: whisker primary sensory cortex (wS1)

We performed extra-cellular recordings simultaneously from the whisker primary sensory cortex (wS1) and the medial prefrontal cortex (mPFC) of mice performing a tactile detection task and then fit a recurrent spiking neural network (RSNN) to the recorded activity. We assume that neural dynamics are defined by standard conductance-based spiking neurons with adaptation. We optimize the entire connectivity matrix (within and across areas) using back-propagation through time (BPTT) for spiking neural networks [1, 2] and synaptic rewiring [3] while respecting Dale’s law. After optimization, the res