Topic: whole-body coordination

Whole-body movements like locomotion require timely and precise coordination of multiple effectors. Moreover, control needs to be robust and flexible to changes in the state of the body and environment. How is such a complex control problem solved by the brain? The cerebellum is critical for coordinating movement; during locomotion it is particularly important for interlimb and whole-body coordination. Decades of recordings have consistently shown that Purkinje cell modulation (the sole output of the cerebellar cortex) is broadly correlated with the locomotor stride cycle. However, much of the