The analyses of neural basis for individual differences in behavioral outcomes caused by long-term social defeat stress in mice
Hibiki Okamura, Shinnosuke Yasugaki, Haruka Suzuki-Abe, Yoshifumi Arai, Katsuyasu Sakurai, Masashi Yanagisawa, Hotaka Takizawa, Yu Hayashi · FENS Forum 2024
Stress susceptibility is highly variable among individuals. For those with high stress susceptibility, they have a high risk of developing mental disorders such as depression upon exposure to social stress. Mice also show depression-like behavior following social stress, and the extent of behavioral changes are variable among individuals even under a uniform genetic background. The precise mechanisms that underlie variability in stress resilience among individuals are poorly understood. To elucidate the mechanisms, we focused on the long-term effects of repeated social defeat stress (SDS) in B
ePoster · Neuroscience