Response modulation dynamics of multi-electrode stimulation in the mouse visual cortex under two-photon microscopy
Kayeon Kim, Alexandra Katherine Isis Yonza, Xiyuan Liu, Anpan Han, Shelley Fried, Changsi Cai · FENS Forum 2024
Multi-electrode stimulation aims to induce sophisticated brain perception by eliciting specific spatial and temporal patterns of neural activity corresponding to sensory perceptions[1][2][3]. However, conventional implanted microelectrode stimulation often results in large-scale brain responses, from a few hundred microns to a few millimeters[2]. This spread of signals may lead to complex signal interactions and integration across adjacent electrodes.In our study, we positioned two monopolar micro-electrodes at various spacings ranging from 400 to 800µm between them, and simultaneously stimula
ePoster · Neuroscience