Comparison of acetylcholine release in the mouse cerebral cortex in response to standard visual stimuli vs dynamic virtual reality environment
Julie Azrak, Hossein Sedighi, Jose Daniel Tirado Ramirez, Yulong Li, Elvire Vaucher · FENS Forum 2024
Acetylcholine (ACh), a potent neuromodulator in the central nervous system, plays a pivotal role in visual processing, attention, and cognitive flexibility. Most of the studies have been using standard visual stimuli, but the advance of virtual reality (VR) tools is promising for better elucidating the dynamics of this neuromodulator in visually guided behaviors. The present study aims to explore the spatiotemporal activation of cortical cholinergic fibers during the presentation of a VR dynamic environment compared to standard visual stimuli using mesoscopic ACh imaging in awake mice.Choliner
ePoster · Neuroscience