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Topic: widefield Ca2+ imaging

ePoster
1 ePoster

In Neuroscience

Large-scale geometry of cortical dynamics underlying evidence accumulation and short-term memory

Renan Costa, Peter Salvino, Jiaqi Luo, Shawna Ibarra, Lucas Pinto · COSYNE 2025

Real-world decisions often require combining different cognitive computations. Recent findings suggest that, on the one hand, these computations are distributed across the cortex. On the other hand, cortical microcircuits seem to implement them via (near) orthogonal population-activity patterns. But how are these local geometries combined at the level of cortex-wide dynamics? To answer this, we developed a new task for mice navigating in virtual reality (VR) to temporally disentangle different cognitive computations. Mice first accumulate evidence to determine the predominant color of a random

ePoster · Neuroscience