Long-term consequences of cannabinoid receptor activation during adolescence on PFC network activity and cognitive functions
Anaïs Notario Reinoso, Helmut Kessels, Pascal Chameau · FENS Forum 2024
Cannabis consumption, particularly among adolescents, has surged over the last decades. Adolescence is a critical period for brain development during which the prefrontal cortex (PFC) completes its maturation. There is strong evidence that the endocannabinoid system is a key regulator of brain development and of maturation of the PFC during adolescence. However, whether chronic cannabinoid receptor activation during this stage of development has long-term consequences for PFC function and associated behaviors remains unexplored. Here we show that repeated injection of cannabinoid receptor agon
ePoster · Neuroscience