Topic: Wistar albino rats

Sexual dimorphism of the developing brain raises the question that early seizures could have distinct effects in immature males and females. This study focuses on the short- and long-term effects of repeated neonatal flurothyl-induced seizures on behavioral responses in male and female rats. A total of 33 Wistar albino rats were used: 17 males (8 controls, 9 treated) and 16 females (7 controls, 9 treated). Animals were repeatedly tested at juvenile and adult ages. At postnatal day 6, the pups were separated from mothers for ~10 minutes (treated: 5 min flurothyl exposure until generalized tonic