Not all-or-nothing: Intracellular action potential waveform varies systematically with extracellular gamma oscillatory state
Blanca Martin-Burgos, Pamela Riviere, Ryan Hammonds, Bradley Voytek · FENS Forum 2024
Individual neurons’ action potentials (APs) have a dynamic waveform, the shape of which differs by neuron subtype and species. In analyses of single-unit data, however, this waveform is reduced to a binary “all-or-nothing” event, with systems and cognitive neuroscience focusing on the number and timing of spike events. This analytical convenience has, in turn, resulted in computational theories of neural coding that assume binarity.Despite this assumption, a considerable body of evidence shows that AP waveforms exhibit systematic, within-neuron variation that may contribute additional informat
ePoster · Neuroscience