Topic: Xenopus metamorphosis

To parse the neural basis of motor behavior, we leveraged the unique swim-to-walk transition of the Xenopus metamorphosis. This transition enabled us to dissect the spinal circuitry underlying tail and limb-based movement. We combined a robust behavioral assay with molecular cell-type profiling in wild-type, and then loss-of-function mutant, tadpoles to evaluate how neuronal diversity scaled with and contributed to the observed increase in movement complexity.We devised a high-speed behavioral setup to track frog’s body parts, quantify complex movement, and create locomotor profiles correlated