Discovering plasticity rules that organize and maintain neural circuits
David Bell, Alison Duffy, Adrienne Fairhall · COSYNE 2025
Intrinsic dynamics within the brain can accelerate learning by providing a prior scaffolding for dynamics aligned with task objectives. Such intrinsic dynamics should self-organize and self-sustain in the face of fluctuating inputs and biological noise, including synaptic turnover and cell death. An example of such dynamics is the formation of sequences, a ubiquitous motif in neural activity. The sequence-generating circuit in zebra finch HVC provides a reliable timing scaffold for motor output in song and demonstrates a remarkable capacity for unsupervised recovery following perturbation. Ins
ePoster · Neuroscience