3 results
Develop a quantitative single-molecule imaging platform for drug discovery with Steven F. Lee. The initial focus is alpha-synuclein aggregation in Parkinson’s disease. Responsibilities include assay development, higher-throughput compound screening, image-analysis pipelines and coordination with academic and commercial partners. The role also contributes to…
Develop theory and computational methods for complex biomolecular systems in Helmut Grubmüller’s group. Topics include variational free-energy methods, solvation-shell thermodynamics, constant-pH simulations and Markovian thermodynamics, with applications to ribosomes, fatty-acid synthase, CRISPR systems and intrinsically disordered proteins. Doctoral…
Help establish Leif-Thore Deck’s new research group and investigate biomolecular phase transitions across scales. The work combines droplet microfluidics and fluorescence microscopy with thermodynamic and kinetic measurements of protein and peptide condensates, fibrils and crystals, connecting microscopic nucleation processes to litre-scale precipitation.…
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