Impaired cardiorespiratory responses to hypercapnia in a chronic model of temporal lobe epilepsy
Ayse Dereli, Auriane Apaire, Enrique Germany and Riem El Tahry
FENS Forum 2024
Respiratory dysfunction, particularly central apnea, accompanied by cardiac abnormalities are proposed to be the underlying causes of Sudden Unexpected Death in Epilepsy (SUDEP). Apnea in SUDEP is characterised by prologued hypercapnia with severe hypoventilation. We propose that this implies an impairment at the…