TopicNeuroscience
Content Overview
8Total items
5ePosters
3Seminars

Latest

SeminarNeuroscienceRecording

Designing the BEARS (Both Ears) Virtual Reality Training Package to Improve Spatial Hearing in Young People with Bilateral Cochlear Implant

Deborah Vickers
Clinical Neurosciences
Oct 11, 2022

Results: the main areas which were modified based on participatory feedback were the variety of immersive scenarios to cover a range of ages and interests, the number of levels of complexity to ensure small improvements were measured, the feedback and reward schemes to ensure positive reinforcement, and specific provision for participants with balance issues, who had difficulties when using head-mounted displays. The effectiveness of the finalised BEARS suite will be evaluated in a large-scale clinical trial. We have added in additional login options for other members of the family and based on patient feedback we have improved the accompanying reward schemes. Conclusions: Through participatory design we have developed a training package (BEARS) for young people with bilateral cochlear implants. The training games are appropriate for use by the study population and ultimately should lead to patients taking control of their own management and reducing the reliance upon outpatient-based rehabilitation programmes. Virtual reality training provides a more relevant and engaging approach to rehabilitation for young people.

SeminarNeuroscience

Improving Communication With the Brain Through Electrode Technologies

Rylie Green
Imperial College London
Oct 27, 2021

Over the past 30 years bionic devices such as cochlear implants and pacemakers, have used a small number of metal electrodes to restore function and monitor activity in patients following disease or injury of excitable tissues. Growing interest in neurotechnologies, facilitated by ventures such as BrainGate, Neuralink and the European Human Brain Project, has increased public awareness of electrotherapeutics and led to both new applications for bioelectronics and a growing demand for less invasive devices with improved performance. Coupled with the rapid miniaturisation of electronic chips, bionic devices are now being developed to diagnose and treat a wide variety of neural and muscular disorders. Of particular interest is the area of high resolution devices that require smaller, more densely packed electrodes. Due to poor integration and communication with body tissue, conventional metallic electrodes cannot meet these size and spatial requirements. We have developed a range of polymer based electronic materials including conductive hydrogels (CHs), conductive elastomers (CEs) and living electrodes (LEs). These technologies provide synergy between low impedance charge transfer, reduced stiffness and an ability to be provide a biologically active interface. A range of electrode approaches are presented spanning wearables, implantables and drug delivery devices. This talk outlines the materials development and characterisation of both in vitro properties and translational in vivo performance. The challenges for translation and commercial uptake of novel technologies will also be discussed.

SeminarNeuroscienceRecording

What is the function of auditory cortex when it develops in the absence of acoustic input?

Steve Lomber
McGill University
Oct 14, 2021

Cortical plasticity is the neural mechanism by which the cerebrum adapts itself to its environment, while at the same time making it vulnerable to impoverished sensory or developmental experiences. Like the visual system, auditory development passes through a series of sensitive periods in which circuits and connections are established and then refined by experience. Current research is expanding our understanding of cerebral processing and organization in the deaf. In the congenitally deaf, higher-order areas of "deaf" auditory cortex demonstrate significant crossmodal plasticity with neurons responding to visual and somatosensory stimuli. This crucial cerebral function results in compensatory plasticity. Not only can the remaining inputs reorganize to substitute for those lost, but this additional circuitry also confers enhanced abilities to the remaining systems. In this presentation we will review our present understanding of the structure and function of “deaf” auditory cortex using psychophysical, electrophysiological, and connectional anatomy approaches and consider how this knowledge informs our expectations of the capabilities of cochlear implants in the developing brain.

ePosterNeuroscience

Synaptic and mesoscale plasticity in auditory cortex of rats with cochlear implants

Ariel Edward Hight,Erin Glennon,Silvana Valtcheva,Mario A. Svirsky,Robert Froemke

COSYNE 2022

ePosterNeuroscience

Synaptic and mesoscale plasticity in auditory cortex of rats with cochlear implants

Ariel Edward Hight,Erin Glennon,Silvana Valtcheva,Mario A. Svirsky,Robert Froemke

COSYNE 2022

ePosterNeuroscience

Good Interaural Time Difference (ITD) Sensitivity with Bilateral Cochlear Implants Requires ITDs in Pulse Timing, Not Envelopes

Nicole Rosskothen-Kuhl, Alexa N. Buck, Lakshay Khurana, Jan W. Schnupp
ePosterNeuroscience

How do Interaural Time and Interaural Level Differences Interact in Spatial Hearing with Cochlear Implants?

Sarah Buchholz, Felix Kleinschroth, Heika Hildebrandt-Schönfeld, Theresa A. Preyer, Jan W. Schnupp, Nicole Rosskothen-Kuhl
ePosterNeuroscience

Optogenetic stimulation reduces spectral spread of cochlear implants – a modeling study

Lakshay Khurana, Daniel Keppeler, Lukasz Jablonski, Tobias Moser

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