Wearable sensors that detect and quantify biomarkers in retrievable biofluids (e.g., interstitial fluid, sweat, tears) provide information on human dynamic physiological and psychological states. This information can transform health and wellness by providing actionable feedback. Due to outdated and insufficiently sensitive technologies, current on-body sensing systems have capabilities limited to pH, and a few high-concentration electrolytes, metabolites, and nutrients. As such, wearable sensing systems cannot detect key low-concentration biomarkers indicative of stress, inflammation, metabolic, and reproductive status.  We are revolutionizing sensing. Our electronic biosensors detect virtually any signaling molecule or metabolite at ultra-low levels. We have monitored serotonin, dopamine, cortisol, phenylalanine, estradiol, progesterone, and glucose in blood, sweat, interstitial fluid, and tears. The sensors are based on modern nanoscale semiconductor transistors that are straightforwardly scalable for manufacturing. We are developing sensors for >40 biomarkers for personalized continuous monitoring (e.g., smartwatch, wearable patch) that will provide feedback for treating chronic health conditions (e.g., perimenopause, stress disorders, phenylketonuria). Moreover, our sensors will enable female fertility monitoring and the adoption of more healthy lifestyles to prevent disease and improve physical and cognitive performance.

A single person can be the source of billions of data points, whether these are generated from everyday internet use, healthcare records, wearable sensors or participation in experimental research. This vast amount of data can be used to make predictions about people and systems: what is the probability this person will develop diabetes in the next year? Will commit a crime? Will be a good employee? Is of a particular ethnicity? Predictions are simply represented by a number, produced by an algorithm. A single number in itself is not biased. How that number was generated, interpreted and subsequently used are all processes deeply susceptible to human bias and prejudices. This session will explore a philosophical perspective of data ethics and discuss practical steps to reducing statistical bias. There will be opportunity in the last section of the session for attendees to discuss and troubleshoot ethical questions from their own analyses in a ‘Data Clinic’.