The International Symposium on Chromaffin Cell Biology is a biennial meeting on adrenal chromaffin cells and their wider relevance to cellular and neurobiological function, held since 1982. The 23rd edition, organised at the University of Innsbruck, links the field's strengths in secretion biology and excitation–secretion coupling with developmental biology, neuroendocrine disease and new technologies. It treats the chromaffin cell both as a classical model of regulated secretion and as a model for neuroendocrine development, stress adaptation and disease. Preliminary themes are excitation–secretion coupling; vesicle biology and regulated secretion; chromogranins and secretory cargo; development, plasticity and regeneration; stress physiology and disease, including pheochromocytoma, paraganglioma and neuroblastoma; and emerging technologies such as single-cell omics, lineage tracing, advanced imaging, electrophysiology and organoids. Studies of related neuroendocrine and secretory systems, from neurons to endocrine and immune cells, are welcome. The programme will include plenary and invited lectures, abstract-selected talks, poster sessions, workshops and early-career opportunities. Typical attendance is 120–180 participants.