ePoster

Fronto-temporal interactions in associative recall explored by multielectrode recordings

Bálint Varga, Marcell Stippinger, Fülöp Bazsó, Attila Bencze, Zoltán Somogyvári, László Négyessy, Hisashi Tanigawa, Tamás Kiss
FENS Forum 2024(2024)
Messe Wien Exhibition & Congress Center, Vienna, Austria

Conference

FENS Forum 2024

Messe Wien Exhibition & Congress Center, Vienna, Austria

Resources

Authors & Affiliations

Bálint Varga, Marcell Stippinger, Fülöp Bazsó, Attila Bencze, Zoltán Somogyvári, László Négyessy, Hisashi Tanigawa, Tamás Kiss

Abstract

Object-based visual working memory relies critically on the fronto-temporal cortical network. Investigating interactions within this network is crucial for comprehending the neural mechanisms of goal-directed recall in memory. A delayed color recall task, wherein colors were associated with achromatic images of scenes and geometric drawings, was employed to examine interactions between the temporal and prefrontal cortex through high-density electrocorticography (ECoG) in two macaque monkeys. Regions with similar functionality were identified by clustering the time-varying signal of electrodes in the ECoG arrays over the prefrontal and temporal cortices. The clustering results aligned with the dorso-ventral and rostro-caudal functional segregation of cortical areas. Analysis of task-specific sub-regional activities revealed a dynamically changing pattern throughout the task in both the temporal and prefrontal cortices. Granger causality analysis in various frequency bands explored the relationship of sub-regional activities within and between the two cortical regions. Mnemonic activities showed higher interregional causal relationships between regions than within them, specifically in the theta and alpha bands, while these differences largely diminished at higher frequencies. Similar observations were noted during the cue period. Phase-Amplitude Coupling (PAC) analysis is underway to gain a deeper understanding of the oscillatory dynamics of fronto-temporal interactions during goal-directed recall in memory.

Unique ID: fens-24/fronto-temporal-interactions-associative-22e8e50a