The main goal of the project is to define the neuro/gliogenesis during normal development of human cortex and to create immunophenotypic maps of human cortex morphogenesis.Cellular differentiation using key markers specific for neural and glial lineages, as well as antibodies to transcription factors and functional proteins of nervous system were studied on the material from the Collection of prenatal human development of AP. Avtsyn Research Institute of Human Morphology, Moscow. In 2021, the online project dedicated to the Collection had been granted by the FENS History Committee(https://brainmicroscopy.com/en/collection/homo/brain-development/).The further project is dedicated to creating a first digital multimodal atlas of human brain development. To date, the project website (https://brainmorphology.science/) provides general information, descriptions of the main materials and methods, brief reference and micrographs of the histological serial sections and immunohistochemical preparations, and atlases of the human fetal brain at 10-26 gestational weeks. Gradually, we hope to obtain spatiotemporal patterns of key protein distributions during neuronal and glial differentiation in the human developing cortex.The most of recent original experiments are focused on identifying the regulatory patterns of the transcriptome during the brain development. However, the transcriptional product occurrence does not always lead to translation, and thus, it is not always possible to predict the functioning (or even the presence) of a protein product in the cell solely by transcriptional activity. We anticipate that cortical immunophenotypic profiling will be useful as a comparative source for a wide range of developmental neuroscience studies.Study is supported by the RSF grant #22-15-00172.