ePoster

Retrieval inhibition during sensorimotor consolidation modulates memory retention

Masuto Ryosuke, Atsuo Nuruki, Tomohiro Nobe, Takumi Tsukada, Koyuki Ikarashi, Hikaru Nuruki, Koya Yamashiro, Genta Ochi, Tomomi Fujimoto, Daisuke Sato
FENS Forum 2024(2024)
Messe Wien Exhibition & Congress Center, Vienna, Austria

Conference

FENS Forum 2024

Messe Wien Exhibition & Congress Center, Vienna, Austria

Resources

Authors & Affiliations

Masuto Ryosuke, Atsuo Nuruki, Tomohiro Nobe, Takumi Tsukada, Koyuki Ikarashi, Hikaru Nuruki, Koya Yamashiro, Genta Ochi, Tomomi Fujimoto, Daisuke Sato

Abstract

Retrieval inhibition (RI), denoting the intentional suppression of recalling specific occurrences, modulates memory retention subsequent to the learning phase. Nonetheless, the impact of RI throughout the process of memory consolidation has remained an area of ambiguity. This investigation examine the effect of RI applied during the consolidation phase on the retention of sensorimotor adaptation.Sixty-two healthy individuals were enlisted for this study. They were randomly assigned to three groups based on the prescribed protocol for memory consolidation: NF, NH, and RI group. All participants engaged in 96 trials of the four-direction forcefield adaptation reaching task for skill acquisition. Subsequently, participants in the NF and NH groups undertook 96 and 48 identical tasks, respectively, for the purpose of memory consolidation. Conversely, individuals in the RI group performed 48 trials of the same task and 48 trials of the RI task. During the RI task, participants were directed to abstain from executing the reaching motion when confronted with directions divergent from those encountered during the skill acquisition phase. The retention of sensorimotor adaptation was evaluated immediately and 24 hours after memory consolidation.LMM significantly revealed superior retention of sensorimotor adaptation twenty-four hours later in both the NF and RI groups, in contrast to the NH group (Figure 1). Moreover, the retention observed within the RI group was commensurate with that of the NF group.These findings suggested that RI, when incorporated during the phase of sensorimotor memory consolidation, facilitates enhanced retention of memory as opposed to mere repetition for an equivalent duration.

Unique ID: fens-24/retrieval-inhibition-during-sensorimotor-b4310824