Short-term plasticity (STP) is the neuronal substrate for modification of the efficiency of synaptic transmission in the timescale of milliseconds to seconds. STP renders synapses the ability to process and integrate inputs which in-turn controls information flow and processing in networks. Our work explored the diversity in STP of hippocampal CA1 synapses and the summation of multiple inputs during STP in a CA1 neuron with balanced excitation and inhibition. We performed invitro experiments on the CA3-CA1 network in acute hippocampal slices from mice expressing channelrhodopsin specifically in CA3 neurons. We achieved spatio-temporally patterned stimulation of randomly chosen sets of CA3 neurons using optogenetics with each spot in the pattern scaled to match the size of a CA3 cell body. Patterned light stimulation was carried out at the CA3 network while CA1 responses were recorded using whole-cell patch-clamp. Using patterned stimulation of the CA3 network, we measured STP in different sets of synapses on CA1 neurons using a paired pulse test at 50 ms interval. While electrode based field stimulation gave overall facilitation, spatially patterned light stimulation gave diverse STP profiles ranging from facilitation to depression. STP depended on the initial weights of the synapses and their excitatory or inhibitory nature. Interestingly, higher stimulus strengths elicited strong short-term depression in inhibition. By controlling the number of spots in light patterns we observed sublinear summation in CA1 neurons. Our results provide insights into the neuronal computation capabilities of CA1 cells with implications for timing, memory and excitation-inhibition balance of the CA3-CA1 network.