Neural stem cell and tissue transplantation offers a promising strategy for central nervous system regeneration. Previous studies have yet to evaluate how the host brain environment in the context of aging effects the ability of the graft to survive and integrate following implantation. The aim of this study was to determine the impact of recipient age on the integration of rat embryonic neural progenitor cells implanted near the subventricular zone (SVZ)-CSF interface. Specifically, embryonic rat neural progenitor cells were implanted near the SVZ of 3-week, 4-month, and 12-month-old rats. The progenitor cells developed into an integrated brain-like tissue in all three age groups and neurons derived from the implanted cells sent long range projections into the host olfactory bulb, cortex, striatum, and thalamus. Regardless of the age of the recipient animal, the implanted cells developed into a similar ratio of neuronal cell types. The cellular composition of the transplant-derived tissue was like that of the cortex as found with immunofluorescent staining. The host brain developed long-distance axons projecting into the transplant derived tissue. Through tracing with retrograde AAV, we found that the host axons innervating the new tissue growth originated primarily in the prefrontal cortex and thalamus. This innervation decreased with increasing age at time of implantation, but some retrograde tracing was seen even in the 12-month cohort. This demonstrates the potential of the adult brain to form new, long-range connections with transplant derived tissue and the ability of implanted neural progenitor cells to mature even in an aged environment.