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AXONAL REGENERATION UNDER AN ELECTRICAL STIMULATION AFTER SCIATIC NERVE INJURY
Hafsa Er-Rouassiand 3 co-authors
CNRS
FENS Forum 2026 (2026)
Barcelona, Spain
Board PS04-08PM-129
Presentation
Date TBA
Board: PS04-08PM-129
Event Information
Poster Board
PS04-08PM-129
Poster
View posterAbstract
Peripheral nerve injuries constitute a major clinical challenge due to the inherently limited regenerative capacity of the nervous system. Despite significant advancements in surgical techniques, functional recovery frequently remains insufficient. Among emerging therapeutic strategies, the application of electrical stimulation has emerged as a promising modality for promoting axonal regeneration through modulation of critical cellular mechanisms. In this study, we assessed the efficacy of targeted neurostimulation in sciatic nerve regeneration following transection. Comprehensive behavioral assessments and detailed analysis of intramuscular reinnervation were performed to evaluate both functional and morphological recovery metrics. Our findings reveal that this electrical intervention exerts a substantial positive influence on neural and muscular recovery, indicating that this treatment significantly enhances these processes. These results support a potential use of electrical stimulation as innovative intervention for peripheral nerve repair and lay foundational groundwork for their prospective clinical implementation.
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