Poster preview
ePoster
THE HUMAN INTESTINAL BACTERIA PHASCOLARCTOBACTERIUM FAECIUM DECREASES MOTIVATION FOR PALATABLE FOOD AND REDUCES DAILY FOOD INTAKE IN FEMALE AND MALE MICE
Carlos Pomares-Díazand 3 co-authors
Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC)
FENS Forum 2026 (2026)
Barcelona, Spain
Board PS02-07PM-019
Presentation
Date TBA
Board: PS02-07PM-019
Event Information
Poster Board
PS02-07PM-019
Poster
View posterAbstract
The human intestinal bacterium Phascolarctobacterium faecium has anti-obesity properties coupled with metabolic benefits in a mouse model of diet-induced obesity. However, a deeper understanding of how this bacterium modulates feeding behaviour is still required. In the present work, we investigated the impact of P. faecium administration on the motivation for palatable food and on circadian patterns of high-fat diet intake. Female and male mice fed control diet received a daily oral dose of P. faecium for 11 weeks and motivation for palatable reward was studied using an operant conditioning procedure. Additionally, circadian patterns of food intake were explored in female and male mice fed an obesogenic diet after 4 weeks of P. faecium treatment. We found that P.faecium reduced motivation for palatable food in both male and female mice. Furthermore, analysis of feeding patterns under an obesogenic diet revealed that P.faecium treated mice showed reduced food intake during both active and inactive phase, especially in females. These results suggests that P.faecium confers metabolic benefits by modulating food-motivated behaviour and feeding patterns positioning this bacterium as a promising probiotic for promoting healthy eating behaviors.
Recommended posters
SEX-SPECIFIC MODULATION OF THE GUT–BRAIN AXIS BY PROBIOTICS IN A MOUSE MODEL OF BINGE EATING DISORDER
Luciene Vieira, Gabriella Malta, Lidia Parreira, Samantha de Oliveira, Clara Diniz, Natsumi Santana, Ana Luisa De Morais, Flaviano Martins
TARGETING THE GUT–BRAIN AXIS TO MODULATE FOOD ADDICTION–LIKE BEHAVIOUR: EFFECTS OF LACTULOSE AND RHAMNOSE
Sena Nur Yucelli, Zeina Msheik, Elena Martín-García, Rafael Maldonado
TARGETING GUT MICROBIOTA COUNTERACTS HIGH-FAT DIET–DRIVEN BEHAVIOURAL AND MOTOR ALTERATIONS IN EAE MICE
Antonio Fiorenza, Federica Palmerio, Sara Balletta, Alessandra Musella, Alice Tartacca, Fabrizio Mariani, Adriana la Candia, Diego Fresegna, Emanuele Claudio Latagliata, Silvia Caioli, Valentina Rovella, Georgia Mandolesi, Diego Centonze, Francesca De Vito
SEX-DEPENDENT RESPONSES TO THE FAT-TASTE ENHANCER NKS-3 IN A MURINE MODEL OF DIET-INDUCED OBESITY
Lucas Jantzen, Cassandre Morisset, Bahrie Ramadan, Christophe Houdayer, Aziz Hichami, Naim Khan, Lidia Cabeza, Vincent Van Waes
GUT-BRAIN AXIS: THE ROLE OF GLP1R-VAGAL AFFERENTS IN THE EFFECT OF DIETARY FIBER ON ENERGY BALANCE
Nadine Eliasson, Chaitanya K. Gavini, Virginie Mansuy-Aubert
MULTIMODAL CHARACTERIZATION OF BINGE EATING DISORDER IN WILD-TYPE MICE: BEHAVIORAL, PROTEOMIC AND GUT MICROBIOTA (16S RRNA) ANALYSES
Paula Acevedo-Hernández, Ute Woehlbier, Gonzalo Jorquera, Pablo Moya