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ePoster
PRENATAL EXPOSURE TO NANOPLASTICS: NEUROINFLAMMATION AND COGNITIVE IMPAIRED IN OFFSPRING
Mojtaba Ehsanifar
Mojtaba Ehsanifar
FENS Forum 2026 (2026)
Barcelona, Spain
Board PS01-07AM-262
Presentation
Date TBA
Board: PS01-07AM-262
Event Information
Poster Board
PS01-07AM-262
Poster
View posterAbstract
The increase in plastic production worldwide makes the environmental threat posed by microplastics, which originate from large amounts of plastic waste, increasingly significant. These small plastic particles are prevalent among various organisms in different ecosystems, raising concerns about their potential effects. In this study, we investigated how polystyrene nanoplastics affect the development of the central nervous system. We studied mice exposed to nanoplastics during their development to study these effects. Our findings show that when nanoplastics are administered to mothers during pregnancy and lactation, they disrupt the normal function of NSCs, alter the composition of nerve cells, and alter the brain structure of their offspring. Furthermore, we discovered that exposure to significant concentrations of nanoplastics during development leads to abnormal brain development that leads to gender-specific neurophysiological and cognitive impairments. This suggests that exposure to high levels of nanoplastics could increase the risk of neurodevelopmental disorders.
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