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ePoster
IS THERE ANY CORRELATION BETWEEN STRIATAL CIT UPTAKE AND COGNITIVE FUNCTION IN PARKINSON’S DISEASE
Oh Dae Kwon
Daegu Catholic University Medical Center
FENS Forum 2026 (2026)
Barcelona, Spain
Board PS06-09PM-635
Presentation
Date TBA
Board: PS06-09PM-635
Event Information
Poster Board
PS06-09PM-635
Poster
View posterAbstract
Aims
This research aimed to investigate any relationship between the decline in receptor uptake of CIT and cognitive symptoms in Parkinson’s disease.
Methods
Fifty-one patients with Parkinson’s disease were recruited from the CIT-PET registry of Daegu Catholic University Medical Center. Diagnosis of Parkinson’s disease was based on the United Kingdom Parkinson’s Disease Brain Bank Criteria and the result of CIT-PET. The striatum was divided into 4 parts: right caudate nucleus, left caudate nucleus, right putamen, left putamen. The uptake of CIT was assessed visually by a nuclear physician, and the scores were summed for each patient. Cognitive symptoms, including attention, language, visuospatial function, memory, and frontal executive function, were measured with the Seoul Neuropsychological Screening Battery by a neuropsychologist. We investigated any correlation between the sum of CIT uptake of each part and cognitive decline using statistical analysis.
Results
A positive correlation was found between CIT uptake decline and cognitive decline, particularly in visuospatial function, memory, and frontal executive function.
Conclusions
We found that a decline in striatal CIT uptake is correlated with cognitive dysfunctions in patients with Parkinson’s disease.
This research aimed to investigate any relationship between the decline in receptor uptake of CIT and cognitive symptoms in Parkinson’s disease.
Methods
Fifty-one patients with Parkinson’s disease were recruited from the CIT-PET registry of Daegu Catholic University Medical Center. Diagnosis of Parkinson’s disease was based on the United Kingdom Parkinson’s Disease Brain Bank Criteria and the result of CIT-PET. The striatum was divided into 4 parts: right caudate nucleus, left caudate nucleus, right putamen, left putamen. The uptake of CIT was assessed visually by a nuclear physician, and the scores were summed for each patient. Cognitive symptoms, including attention, language, visuospatial function, memory, and frontal executive function, were measured with the Seoul Neuropsychological Screening Battery by a neuropsychologist. We investigated any correlation between the sum of CIT uptake of each part and cognitive decline using statistical analysis.
Results
A positive correlation was found between CIT uptake decline and cognitive decline, particularly in visuospatial function, memory, and frontal executive function.
Conclusions
We found that a decline in striatal CIT uptake is correlated with cognitive dysfunctions in patients with Parkinson’s disease.
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