Data ScientistApplications Closed
Albert Cardona
United Kingdom, Cambridge
Apply by Nov 5, 2020
Application deadline
Nov 5, 2020
Job
Job location
Albert Cardona
United Kingdom, Cambridge
Geocoding in progress.
Source: legacy
Quick Information
Application Deadline
Nov 5, 2020
Start Date
Flexible
Education Required
See description
Experience Level
Not specified
Job
Job location
Albert Cardona
Job Description
To work within the group of Dr Albert Cardona at the MRC Laboratory of Molecular Biology (LMB), within a programme aimed at whole brain connectomics from volume electron microscopy. Specifically, we are seeking to recruit a data scientist with at least a year of experience with densely labelled volume electron microscopy data of nervous tissue. In particular, the candidate will be experienced in developing and applying machine learning frameworks for synapse detection and segmentation, neuron segmentation and proofreading, and quantification of neuronal structures in nanometre-resolution data sets imaged with volume electron microscopy, for the purpose of mapping neuronal wiring diagrams from volume electron microscopy. The ideal candidate will have an academic track record in the form of authored publications in the arXiv, computer vision conferences, and scientific journals, as well as accessible source code repositories demonstrating past work.
The ideal candidate will have experience with the python programming language (at version 3+), and in the use of machine learning libraries with python bindings such as keras or pytorch, and has written code available in accessible source code repositories where it can be evaluated by third parties, and has deployed their code to both CPU and GPU clusters, and single servers with multiple GPUs. The ideal candidate has applied all of the above towards the generation of over-segmentations of neuronal structures, and is familiar with approaches for post-processing (proofreading) to automatically agglomerate over-segmented neuron fragments into full arbors, using biologically grounded approaches such as microtobule or endoplasmatic reticulum segmentation for validation.
The ideal candidate will have experience with the python programming language (at version 3+), and in the use of machine learning libraries with python bindings such as keras or pytorch, and has written code available in accessible source code repositories where it can be evaluated by third parties, and has deployed their code to both CPU and GPU clusters, and single servers with multiple GPUs. The ideal candidate has applied all of the above towards the generation of over-segmentations of neuronal structures, and is familiar with approaches for post-processing (proofreading) to automatically agglomerate over-segmented neuron fragments into full arbors, using biologically grounded approaches such as microtobule or endoplasmatic reticulum segmentation for validation.
Requirements
- Essential:
- Background in computer vision and machine learning
- or a closely related field. The ideal candidate will have a mixed background of neuroscience and mathematics
- statistics
- engineering or a related field strongly grounded in applied math in the other.
- Experience in software engineering
- particularly with python
- and the crafting of programs and pipelines using libraries such as Django
- keras
- torch
- scikit-learn
- and related machine learning and computer vision libraries.
- Experience in JavaScript for front-end UI development
- and importantly with writing programs for GPU-based computing.
- Experience with running programs in CPU and GPU clusters
- debugging them
- collating results.
- Experience in connectomics
- in particular neuronal arbor reconstruction using manual and semi-automated methods
- proofreading
- and automated synapse detection.
- Familiar with connectomics concepts associated with neurite segmentation
- agglomeration of over-segmentations
- proofreading
- and more.
- Desirable:
- Experience with electron microscopy imagery.
- Experience in systems administration
- backup
- version control
- and data management.
- Experience in the graph-theoretic analysis of neural circuit wiring diagrams.
- General neuroscience knowledge.
Job
Job location
Albert Cardona
Coordinates pending.