The Gatsby Computational Neuroscience Unit is a leading research centre focused on theoretical neuroscience and machine learning. We study (un)supervised and reinforcement learning in brains and machines; inference, coding and neural dynamics; Bayesian and kernel methods, and deep learning; with applications to the analysis of perceptual processing and cognition, neural data, signal and image processing, machine vision, network data and nonparametric hypothesis testing. The Unit provides a unique opportunity for a critical mass of theoreticians to interact closely with one another and with researchers at the Sainsbury Wellcome Centre for Neural Circuits and Behaviour (SWC), the Centre for Computational Statistics and Machine Learning (CSML) and related UCL departments such as Computer Science; Statistical Science; Artificial Intelligence; the ELLIS Unit at UCL; Neuroscience; and the nearby Alan Turing and Francis Crick Institutes. Our PhD programme provides a rigorous preparation for a research career. Students complete a 4-year PhD in either machine learning or theoretical/computational neuroscience, with minor emphasis in the complementary field. Courses in the first year provide a comprehensive introduction to both fields and systems neuroscience. Students are encouraged to work and interact closely with SWC/CSML researchers to take advantage of this uniquely multidisciplinary research environment.