Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA
Job · Posted Sep 29, 2026
Cambridge, United States
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Full-time position
Calico
Connect therapeutic-antibody discovery with computational design. The scientist develops and validates rational antibody designs, structures experimental data to improve models, and collaborates with wet-lab and machine-learning teams on humanisation, affinity, specificity and developability.
Relevant PhD; at least five years of post-PhD antibody/protein engineering experience for Senior Scientist or eight for Principal Scientist. Requires Python, modern protein-design tools and onsite work five days per week.
Source: Calico