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This symposium links molecular mechanisms of maternal-fetal communication with healthy development and pregnancy complications. It examines implantation, placental development, trophoblast differentiation and invasion, decidualisation and spiral-artery remodelling. Immune-cell interactions, endometrial glands, oxygen and nutrient supply are considered alongside mechanisms underlying pregnancy disorders. Stem-cell embryo models, organoids and microphysiological systems are connected with single-cell, spatial and multi-omic measurements, gene editing and bioengineering. The programme welcomes researchers and clinicians across career stages to compare experimental systems and identify questions spanning basic and clinical pregnancy research.
Apr 13–16, 2027
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