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Dr.
Janelia Research Campus
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Schedule
Wednesday, June 24, 2020
4:00 PM Asia/Jerusalem
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Recording provided by the organiser.
Format
Recorded Seminar
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Available
Host
NeuroMath
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Interpreting high-dimensional datasets requires new computational and analytical methods. We developed such methods to extract and analyze neural activity from 20,000 neurons recorded simultaneously in awake, behaving mice. The neural activity was not low-dimensional as commonly thought, but instead was high-dimensional and obeyed a power-law scaling across its eigenvalues. We developed a theory that proposes that neural responses to external stimuli maximize information capacity while maintaining a smooth neural code. We then observed power-law eigenvalue scaling in many real-world datasets, and therefore developed a nonlinear manifold embedding algorithm called Rastermap that can capture such high-dimensional structure.
Carsen Stringer_
Dr.
Janelia Research Campus
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The development of the iPS cell technology has revolutionized our ability to study development and diseases in defined in vitro cell culture systems. The talk will focus on Rett Syndrome and discuss t
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