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Hunger State Dependent Modulation

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SeminarPast EventNeuroscience

Hunger state-dependent modulation of decision-making in larval Drosophila

Katrin Vogt

Dr.

University of Konstanz

Schedule
Monday, October 24, 2022

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Monday, October 24, 2022

4:00 PM Europe/Lisbon

Host: Brain-Body Interactions

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Brain-Body Interactions

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Abstract

It is critical for all animals to make appropriate, but also flexible, foraging decisions, especially when facing starvation. Sensing olfactory information is essential to evaluate food quality before ingestion. Previously, we found that <i>Drosophila</i> larvae switch their response to certain odors from aversion to attraction when food deprived. The neural mechanism underlying this switch in behavior involves serotonergic modulation and reconfiguration of odor processing in the early olfactory sensory system. We now investigate if a change in hunger state also influences other behavioral decisions. Since it had been shown that fly larvae can perform cannibalism, we investigate the effect of food deprivation on feeding on dead conspecifics. We find that fed fly larvae rarely use dead conspecifics as a food source. However, food deprivation largely enhances this behavior. We will now also investigate the underlying neural mechanisms that mediate this enhancement and compare it to the already described mechanism for a switch in olfactory choice behavior. Generally, this flexibility in foraging behavior enables the larva to explore a broader range of stimuli and to expand their feeding choices to overcome starvation.

Topics

cannibalismdecision-makingdrosophilafeeding behaviourfood deprivationhunger stateolfactory informationsensory processingserotonergic modulation

About the Speaker

Katrin Vogt

Dr.

University of Konstanz

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Personal Website

www.neurobiology-konstanz.com/vogt

@KatrinVogt3

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twitter.com/KatrinVogt3

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