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Prof
Northwestern University
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Schedule
Tuesday, April 28, 2020
2:00 PM Europe/London
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Recorded Seminar
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Host
The Neurotheory Forum
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Animals perform learned actions with remarkable consistency for years after acquiring a skill. What is the neural correlate of this stability? We explore this question from the perspective of neural populations. Recent work suggests that the building blocks of neural function may be the activation of population-wide activity patterns: neural modes that capture the dominant co-variation patterns of population activity and define a task specific low dimensional neural manifold. The time-dependent activation of the neural modes results in latent dynamics. We hypothesize that the latent dynamics associated with the consistent execution of a behaviour need to remain stable, and use an alignment method to establish this stability. Once identified, stable latent dynamics allow for the prediction of various behavioural features via fixed decoder models. We conclude that latent cortical dynamics within the task manifold are the fundamental and stable building blocks underlying consistent behaviour.
Sara Solla
Prof
Northwestern University
neuro
neuro
The development of the iPS cell technology has revolutionized our ability to study development and diseases in defined in vitro cell culture systems. The talk will focus on Rett Syndrome and discuss t
neuro
Pluripotent cells, including embryonic stem (ES) and induced pluripotent stem (iPS) cells, are used to investigate the genetic and epigenetic underpinnings of human diseases such as Parkinson’s, Alzhe