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Prof. Dr.
Max Planck Institute for Brain Research
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Schedule
Monday, October 26, 2020
4:00 PM Europe/London
Seminar location
No geocoded details are available for this content yet.
Format
Past Seminar
Recording
Not available
Host
Cortex Club
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No geocoded details are available for this content yet.
The complex morphology of neurons, with synapses located 100’s of microns from the cell body, necessitates the localization of important cell biological machines and processes within dendrites and axons. Using expansion microscopy together with metabolic labeling we have discovered that both postsynaptic spines and presynaptic terminals exhibit rapid translation, which exhibits differential sensitivity to different neurotransmitters and neuromodulators. In addition, we have explored the unique mechanisms neurons use to meet protein demands at synapses, identifying the transcriptome and translatome in the neuropil.
Erin Schuman
Prof. Dr.
Max Planck Institute for Brain Research
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The development of the iPS cell technology has revolutionized our ability to study development and diseases in defined in vitro cell culture systems. The talk will focus on Rett Syndrome and discuss t
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Pluripotent cells, including embryonic stem (ES) and induced pluripotent stem (iPS) cells, are used to investigate the genetic and epigenetic underpinnings of human diseases such as Parkinson’s, Alzhe