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Rigidity Fluidity Biological Tissue

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SeminarPast EventPhysics of Life

“Rigidity and Fluidity in Biological Tissue”

Christina Marchetti

Principal Investigator

University of California, Santa Barbara

Schedule
Monday, November 2, 2020

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Monday, November 2, 2020

12:45 PM America/Chicago

Host: Center for Theoretical Biophysics Seminar

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Past Seminar

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Center for Theoretical Biophysics Seminar

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Abstract

The coordinated migration of groups of cells underlies many biological processes, including embryo development, wound healing and cancer metastasis. In many of these situations, tissues are able to tune themselves between liquid-like states, where cells flow collectively as in a liquid, and solid-like states that can support shear stresses. In this talk I will describe mesoscopic models of cell assemblies inspired by active matter physics to examine the roles of cell motility, cell crowding and the interplay of contractility and adhesion in controlling the rheological state of biological tissue.

Topics

active matter physicsbiological tissuebiophysicscancer metastasiscell migrationcell motilitycontractilityembryo developmentrheological statewound healing

About the Speaker

Christina Marchetti

Principal Investigator

University of California, Santa Barbara

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